18 Awesome Cruise Itineraries You Can Book From North America

Fun Cruise Itineraries From North America
While the cruise industry definitely took a hit during the worst of the pandemic, most cruise lines are already back to normal and doing all they can to lure couples, families and anyone else who wants to cruise back on board. That means offering awesome cruise sales, as well as unique itineraries we may have never seen before. Some cruise lines are even coming up with special cruise deals that can make cruising more affordable or enjoyable, such as free cabin upgrades, onboard credits and free drink and wifi packages on select itineraries.

But, which amazing sailings should you consider if you don’t want to fly out of the United States first? Believe it or not, but some of the most interesting and relaxing cruise itineraries around the world depart from (and return to) North America, but only after taking you on a whirlwind trip you’ll never forget.

Maybe you want to see the wild, natural beauty of Alaska, or perhaps you want to see the lush green mountains of Hawaii. Some of the best cruise itineraries from North America also take you to some of the less popular destinations throughout the Caribbean, or even to far-flung destinations like Bermuda.

No matter what kind of cruise you’re after, you should check out these amazing cruise itineraries from cruise lines like MSC Cruises, Royal Caribbean, Princess Cruises and Virgin Voyages first.

7-Night Alaska Inside Passage from Seattle: Princess Cruises
Travelers who want to see the unmatched natural beauty of Alaska, as well as whales, sea lions and other wildlife, can book this 7-night Inside Passage cruise out of Seattle on Princess Cruises. This Alaska-based itinerary includes stops in Ketchikan, Juneau and Skagway before ending its journey in Vancouver, British Columbia. Travelers will also enjoy a day of scenic cruising along the Endicott Arm Fjord during the trip.

5-Night Dominican Daze from Miami: Virgin Voyages
Richard Branson’s new adults-only cruise line, which is aptly named Virgin Voyages, offers an array of exciting itineraries across Europe and the Caribbean, including their Dominican Daze voyage. This itinerary lasts for five nights and takes travelers to Puerto Plata, Dominican Republic, as well as Virgin Voyages’ Beach Club in Bimini. The sailing also includes two sea days where sailors can enjoy onboard amenities like pools, basketball courts, spa services and the line’s champagne bar.

6-Night Bermuda Cruise from New York City: MSC Cruises
Starting in August of 2022, MSC Cruises will begin offering an array of new itineraries that spend days at a time docked at the stunning island of Bermuda. These sailings will take place on the MSC Meraviglia, and they depart from the cruise line’s new departure port of New York City. The six-night sailing includes two sea days and three full days at King’s Wharf in Hamilton, Bermuda.

7-Night History, Seafood and Nature Reserves from Halifax: Hurtigruten Expeditions
This eight-day expedition takes place on the MS Roald Amundsen, and it lets guests experience all the natural beauty and wonder of the scenic national parks along North America’s stunning Atlantic coast. The cruise ends its journey in Boston, but only after spending time in port in destinations like Lunenburg, Eastport and Acadia National Park

10-Night Jungles & Jewels of the Central American Coast from Miami: Windstar Cruises
This 10-night luxury cruise from Windstar Cruises departs from Miami, Florida before taking travelers on an epic journey throughout Mexico and Central America. Guests will see the beauty of the Caribbean Sea up close and personal, and stops include Key West, Florida, Cozumel and Costa Maya in Mexico along with Belize City, Belize, Roatan, Honduras and Santo Tomas De Castillo in Guatemala.

7-Night Eastern Caribbean Cruise from Miami: MSC Cruises
Starting in December of 2022, MSC Cruises will begin offering sailings on one of their newest ships — the MSC Seascape. This new vessel, which will be named in New York City near the beginning of December 2022, will offer sailings from Miami with stops in destinations like San Juan, Puerto Rico, Puerto Plata in the Dominican Republic and Ocean Cay Marine Reserve in the Bahamas.

7-Night Highlights and National Parks of the Pacific from San Diego: Hurtigruten Expeditions
After embarking the MS Roald Amundsen in San Diego, California, guests on this seven-night Hurtigruten Expeditions itinerary will stop in Santa Barbara and Eureka on their way to Olympia National Park. This itinerary is ideal for whale spotting and exploring nature, as well as visits to the incredible Redwood National Park with its giant and ancient redwoods.

15-Night Hawaiian Hawaii Islands Round-Trip from San Francisco: Princess Cruises
This 15-night cruise itinerary on Princess Cruises’ Ruby Princess lets you see the extraordinary beauty of the Hawaiian islands without having to make a long flight across the Pacific Ocean. Guests will board the round-trip sailing from San Francisco, California, and stops include Kona, Hilo, Oahu and the island of Kauai along with one afternoon in Ensenada, Mexico.

9-Night Southern Caribbean Cruise from Fort Lauderdale: Celebrity Cruises
If you’re hoping to sail from Fort Lauderdale, Florida and looking for a Caribbean itinerary that is longer than normal and somewhat unique, check out this southern Caribbean sailing from Celebrity Cruises. There are four sea days on this itinerary, which gives you plenty of time to relax and explore the Celebrity Equinox, the vessel for this cruise. Stops include some of the most beautiful islands in the Caribbean, from Aruba to Bonaire, Curacao and Grand Cayman.

7-Night Great Lakes Sailing from Toronto: Ponant
Ponant, a leader in small-ship luxury expeditions, is currently offering several seven-night journeys throughout the Great Lakes region of the United States as part of a partnership with the Smithsonian Institution. Departures take place from Toronto, Canada, and the journey takes guests throughout each of the lakes with stops in destinations like Niagara Falls and Mackinac Island.

4-Night Fire & Sunset Soiree from Miami: Virgin Voyages
Virgin Voyages also offers a unique four-night itinerary out of their home port of Miami, which takes sailors to spend the day partying in Key West before embarking on a journey to Virgin Voyages’ Beach Club in Bimini. This itinerary takes place on the cruise line’s Scarlet Lady, and an array of exclusive cabins are available including the line’s RockStar Quarters and MegaRockStar Quarters.

14-Night Panama Canal Cruise from Los Angeles: Royal Caribbean International
This two-week sailing on Royal Caribbean takes travelers to visit an array of unique ports throughout Central America and Mexico, along with a sailing directly through the Panama Canal itself. This itinerary also includes stops in Puerto Vallarta, Mexico, San Juan del Sur, Nicaragua, Puntarenas, Costa Rica and Cartagena, Colombia before ending in New Orleans, Louisiana.

13-Night Transatlantic Cruise from Tampa: Carnival Cruise Line
If you want to depart from North America and end your journey on an entirely different continent, consider booking this 13-night trip with Carnival Cruise Line out of Tampa, Florida. Guests who book this sailing will spend nine days at sea and stop in Barcelona, Malaga and Valencia, Spain, as well as Ponta Delgada, Portugal. That’s a lot of sea days for sure, but travelers can keep themselves busy with Carnival Pride amenities like onboard karaoke, three pools and a large-scale outdoor entertainment zone.

7-Night Inter-Island Hawaii Cruise from Honolulu: Norwegian Cruise Line
If you can find your way to Honolulu, Hawaii on the island of Oahu, you can book this seven-night inter-island cruise on Norwegian Cruise Line any time of the year, all year long. This seven-night itinerary stops on the islands of Maui, Hilo, Kona and Kauai to let you enjoy the trip of a lifetime and some of the most stunning ocean and mountain views in the world.

12-Night Off The Beaten Path Alaska: Princess Cruises
Princess Cruises is also offering a unique itinerary that departs on various dates through September of 2022. This 12-night expedition takes place both at sea and on land, starting with a cruise that stops in Ketchikan, Juneau, Skagway and Anchorage. Guests will also cruise through Glacier Bay National Park and College Fjord before spending five days among America’s greatest wilderness destinations at Kenai Princess Wilderness Lodge, Mt. Mckinley Princess Wilderness Lodge, Denali Princess Wilderness Lodge and Fairbanks.

10-Night Canada and New England from New York: MSC Cruises
Once MSC Cruises begins sailing out of New York City in fall of 2022, new cruises to Canada and New England will become available. For example, the cruise line is offering a 10-night sailing out of New York City in September of 2022 that includes stops in Boston, Newport and Portland before moving on to Canadian destinations like Saint John, Sydney and Charlottetown.

7-Night Mexican Riviera Cruise from Los Angeles: Norwegian Cruise Line
Over several dates from October 2022 throughout parts of 2023 and 2024, Norwegian Cruise Line will offer a seven-night Mexican Riviera cruise from Los Angeles, California on the Norwegian Bliss. This cruise offers six or more hours in every port with stops in Cabo San Lucas, Puerto Vallarta, Mazatlan and Ensenada, Mexico before returning back to the United States.

12-Night Southern Caribbean Cruise from Baltimore: Royal Caribbean International
If you’re looking for a longer cruise and you live within driving distance of Baltimore, Maryland, this 12-night cruise throughout the southern Caribbean could be exactly what you want. There are four sea days in total on this Royal Caribbean itinerary, yet you’ll also stop for relaxing days on the islands of St. Croix, St. Lucia, Barbados, St. Kitts, and St. Maarten before returning to the United States.